Alpha GPC Review – Benefits, Dosage Information, Side Effects, & More

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Alpha-GPC is a world-class, naturally-occuring brain nutrient that is most known for its ability to enhance memory and learning when supplemented.

It’s primarily supplemented as a choline supplement since it can significantly raise levels of acetylcholine in the hippocampus.

Acetylcholine regulates attention and various executive functions and is responsible for higher-ordered consciousness and general mental activity.

 

An Overview of Alpha GPC Benefits

 

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Alpha GPC vs CDP Choline

Both Alpha-GPC and CDP-Choline are highly effective nootropics in their own right and are arguably the best cholinergic nootropics available today.

Both of them pair quite well with the racetam family of nootropic compounds. This is because racetams such as oxiracetam primarily work by utilizing choline in the brain.

However, both of alpha-gpc and cdp-choline have distinguishable qualities which help set them apart from each other, and each of them is a capable nootropic in their own right.

 

Alpha-GPC

Alpha-GPC is in fact the most effective nootropic available today for raising acetylcholine in the brain. In fact, it is even more effective at raising acetylcholine than cdp-choline.7europepmc.org/abstract/med/1428296

It’s extremely effective at improving memory and cognitive functions, and can pair extremely well with choline-depleting racetams such as pramiracetam.

Recent research has indicated it may also cause a short spike of HGH and several neurotransmitters including dopamine and serotonin, however it’s a fairly mild increase and requires a large dose.

 

CDP-Choline

In contrast, CDP-Choline is a more well-rounded nootropic that is better suited for overall brain health. While CDP-Choline does provide a notable amount of acetylcholine to the brain, it is more expensive on a cost-per-dose basis.

However, CDP-Choline actually does more than suppy the brain with choline. It boosts several other key neurotransmitters including dopamine and norepinephrine, which can improve motivation, focus, and enhance mood.

Additionally, CDP-Choline provides some significant long-term benefits to cognition and can be thought of as a super nutrient for brain health.

 

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Alpha GPC Side Effects

When it comes to acetylcholine, sometimes less is more. High levels of acetylcholine can cause headache and can cause a “flat” sort of feeling. This is because acetylcholine can dominate other neurotransmitters in the brain and prevent the release of feel good chemicals such as dopamine.

When taking alpha-gpc, it’s advisable to start with smaller doses to prevent these possible side effects. A good starting dose is 300mg once a day. If combined with a racetam such as pramiracetam, more may be needed.

 

 

 

References

1. https://www.sciencedirect.com/science/article/pii/0091305791900409

2. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4536529/

3. http://www.ncbi.nlm.nih.gov/pubmed/23244432

4. http://www.ncbi.nlm.nih.gov/pubmed/8726961

5. http://www.jissn.com/content/5/S1/P15

6. https://www.ncbi.nlm.nih.gov/pubmed/22673596

7. europepmc.org/abstract/med/1428296

 

 

 

FDA Compliance

The information on this website has not been evaluated by the Food & Drug Administration or any other medical body. We do not aim to diagnose, treat, cure or prevent any illness or disease. Information is shared for educational purposes only. You must consult your doctor before acting on any content on this website, especially if you are pregnant, nursing, taking medication, or have a medical condition.

 

 

 

 

 

 

Review of CDP Choline (Citicoline) – Dosage, Benefits, & Side Effects

Affiliate Disclosure

 

CDP Choline, also called citicoline, is a naturally-occuring nutrient and a highly respected nootropic powerhouse. When supplemented it provides numerous brain health benefits, which including supplying the brain with the neurotransmitter acetylcholine.

 

Citicoline benefits:

 

 

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Our Review of CDP-Choline

CDP-Choline is hands down one of the most effective supplements improving cognitive ability, and the research couldn’t be more clear on this. This is because cdp-choline is actually a naturally-occuring compound that the brain produces, and it knows exactly what to do with it when it’s supplemented.

Citicoline is involved in a complex chain of biochemical reactions in the brain and is a critical component of cell membranes. It protects the brain against damage, including cognitive decline associated with aging.2www.ncbi.nlm.nih.gov/pubmed/17171187

Most notably, cdp choline also supplies the brain with large amounts of acetylcholine. Acetylcholine is one of the most important neurotransmitters for regulating conitive function, especially attention and memory.

Typically, people will seek to supplement choline supplements which the brain uses to synthesize acetylcholine. However, many of these choline supplements are poorly absorbed and have limited effectiveness.

 

Citicoline Dosage Information and Stack Advice

A typical dose is 300mg taken up to 4 times daily. Start with smaller doses and work your way up slowly. A common side effect with choline supplements is a “flat” mood – caused by reflective thoughts overriding emotionality.

Citicoline is synergistic when combined with a racetam such as phenylpiracetam, as racetams tend to utilize significant amounts of acetylcholine in the brain. Higher doses of citicoline may be necessary than normal if taking a racetam.

 

 

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CDP Choline vs Alpha GPC

We strongly believe that cdp-choline and alpha-gpc are hands down the most effective choline-boosting nootropics on the market today.

However, many people often wonder how they compare. The differences between them actually fairly apparent, based on the studies and from user reports on places such as reddit.

CDP-Choline can be thought of a general-purpose nootropic that does a lot more than just boost acetylcholine in the brain. It’s effective both in the short-term and long term: in the short term, it raises acetylcholine, dopamine, and norepinephrine.  In the long term it helps prevent cognitive decline by preserving cellular structures, and can even increase the density of dopamine receptors

In contrast, Alpha-GPC is hands down the most effective nootropic for elevating acetylcholine. As such, it is a world class memory-enhancing nootropic.and there is an increasingly large body of research that shows incredible potential for improving memory and learning processes. Unlike cdp-choline, it does not appear to do much beyond enhancing memory, and it’s unclear if it has any long-term benefits.

In short, if memory enhancement is your primary goal, alpha-gpc is a better choice. And if you’re taking a racetam such as pramiracetam, it may provide more “bang for your buck” in preserving acetylcholine levels.

However, if general cognitive enhancement and long-term brain health is your goal, cdp-choline is the better choice. No doubt, it will also prove to be quite effective when stacked with racetams, and can still supply plenty of acetylcholine with reasonably small doses.

 

 

 

 

References

1. http://www.tandfonline.com/doi/abs/10.1080/01616412.1995.11740327

2. http://www.ncbi.nlm.nih.gov/pubmed/17171187

3. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1908237

 

 

FDA Compliance

The information on this website has not been evaluated by the Food & Drug Administration or any other medical body. We do not aim to diagnose, treat, cure or prevent any illness or disease. Information is shared for educational purposes only. You must consult your doctor before acting on any content on this website, especially if you are pregnant, nursing, taking medication, or have a medical condition.