Fasoracetam is the newest member of the racetam family of nootropics. It is commonly referred as NS-105 as it is still a fairly new substance. This novel racetam was first developed in the 1990s by Japanese scientists, and has since been picked up once again in the 2010s after so many positive user reports.
Benefit of Fasoracetam
It is a rather exotic compound that has some unusual effects on mood and mental function. It has seen considerable interest in nootropics and biohacking communities alike (especially /r/ nootropics on Reddit), and many people report positive benefit, including:
- enhanced mood and motivation
- reduced anxiety and depression
- helps prevent procrastination
- improves memory function
- enhances attention and focus
As of 2019, it shows immense potential for treating ADHD and anxiety disorders.1https://www.ncbi.nlm.nih.gov/pubmed/26366330 This is one of the few safe and non-stimulant drugs that may be able to treat ADHD, and as such it has been gaining more and more attention.
How Does Fasoracetam Work?
Like other racetams, it primarily works by subtly influencing the glutamate system in the brain, leading to a range of benefits. Glutamate is a neurotransmitter which modulates brain activity and synaptic communication2https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2904507/. Overly anxious people tend to have abnormal glutamate function, which may explain why fasoracetam can reduce anxiety.
Fasoracetam also seems to enhance acetycholine activity in the frontal lobes, which leads to improved mental acuity and short-term memory function.
Interestingly, fasoracetam is uniquely able to increase the availability of GABA in the brain.3https://www.ncbi.nlm.nih.gov/pubmed/9272724 GABA is a neurotransmitter which can promote feelings of wellbeing, calmness, positive mood.
Our Final Thoughts
The ability to simultaneously enhance both mood and cognition performance is a unique trait that is hard to come by. Fasoracetam definitely deserves more research and it may prove to be a highly beneficial nootropic substance.
We think it is definitely worth trying, even if your experiences with other racetams were underwhelming. While all the racetam compounds have similar pharmacological actions, many people may respond very strongly to one and not so much to the others. It takes patience to learn what will work best for you.
Fasoracetam Dosage Information
Typical doses are 20mg up to three times daily. Due to the acetylcholine-depleting actions of fasoracetam, we strongly recommend to combining it with choline supplement such as alpha-gpc or cdp-choline.
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